**Responsibilities**:
- Develop and implement scalable mRNA purification strategies, to generate highly pure material.
- Design, develop, and implement workflows for mRNA production.
- Uses a data-driven approach to progress development deliverables.
- Develop robust and scalable downstream processes at the laboratory scale for the purification of nucleic acids with tangential flow filtration and liquid chromatography.
- Perform troubleshooting process performance issues.
- Support scale-up of upstream/downstream processes and technology transfer to the cGMP manufacturing and quality control groups for clinical material production.
- Perform routine bench work under limited supervision, effectively prioritize responsibilities and complete assignments in a timely manner.
- Able to analyze, interpret, and present results to project teams and write technical reports.
- Maintaining domain expertise in new technologies and scientific literature to constantly drive innovation.
**Qualifications**:
**Requirements**:
- Demonstrated experience with standard analytical equipment (plate reader, nanodrop, spectrophotometer, PCR, protein and nucleic acid electrophoresis) and knowledge of molecular biology, biochemistry, and biophysics protocols is required.
- Strong technical expertise in two or more of the following: in vitro transcription (IVT) synthesis, molecular cloning, capillary gel electrophoresis (CGE) high-performance liquid chromatography (HPLC), fast protein liquid chromatography (FPLC), and tangential flow filtration (TFF).
- Experience in upstream processing, including use of bioreactors at small, intermediate, and large scales; familiarity with the process development of mRNA products would be a plus.
- Experience writing content for technical documentation, including SOPs, work instructions, technical protocols and reports, and technical presentations.
- A high level of commitment and a track record of quality work, with attention to detail.
- Capable of communicating the work clearly among the team
- A self-starter and great teammate.