Postdoc - Soskic Lab Genomics Research Centre

HT is an interdisciplinary research institute, created and supported by the Italian government, whose aim is to develop innovative strategies to promote human health through a multidisciplinary and integrated approach, combining genomics, computational and structural biology and neuroscience, as well as data and decision sciences.
Soskic group studies molecular mechanisms that regulate B cell activation, antibody production and their genetic variability ( https://humantechnopole.it/en/research-groups/soskic-group/ ). We use a wide range of immunological and genomic assays to study B cell biology, antibody diversity and variation in the human immune system in health and disease.
We are looking for a candidate with expertise in cellular immunology or immunogenomics.
Key tasks and responsibilities:
Leverage the recent advances in CRISPR, cell imaging and single-cell sequencing technologies to dissect molecular mechanisms regulating B cell activations;
Develop new ideas to measure cell biological phenotypes of B cells and study antibody diversification;
Managing data analysis within their project;
Generating reliable data for publication in the projects to which they are assigned and recording all data and results in specified forms (paper and electronic);
Publishing reproducible research;
Interacting and supporting other group members whenever needed;
Sharing and discussing research results with collaborators.
Job requirements
PhD in immunology, cell biology, genomics or other relevant disciplines (or PhD is going to be awarded by January 2025);
Fluency in English – HT is an international research institute and English will be the main language spoken in the lab.
Preferential requirements:
Experience with B cell isolation, manipulation, activation and culture;
Experience with genomic technologies (e.g. scRNA-seq);
Experience in flow cytometry;
Experience in imaging technologies (e.g. confocal microscopy);
Experience in molecular biology (e.g. CRISPR/Cas9 genome editing).

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