**Site Name**: Italy - Siena
**Posted Date**: Dec 16 2024
The selected post-doc is expected to generate different MAPS, by evaluating the most appropriate chemistry for all GBS polysaccharides to be included in the vaccine. She/he will characterize them, evaluate their purity, initial stability and test them in animal models and compare them with already available glycoconjugates.
**Basic Qualifications & Skills**:
- PhD qualification in chemistry or pharmaceutical chemistry and technology
- Experiences in bacterial polysaccharide and glycoconjugate purification techniques like tangential flow filtration and chromatography (HIC, IEX, SEC).
- Experiences in analysis and characterization of polysaccharides and glycoconjugates, use of techniques like HPLC, HPAEC-PAD, NMR and UV-VIS colorimetric methods.
- Good level of spoken, conversational and written English
**Preferred Qualifications & Skills**:
- Experience with polysaccharide chemical derivatization
- Experience with polysaccharide conjugation chemistry
- Innovative thinking, be able to identify link between different components of a problem or situation related to own work
- Clear and effective communication skills, oral and writing. Ability to present scientific data.
- Experience with immonoassays and molecular biology (as a plus)
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GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
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